EXHIBIT 5 OPINION OF HORWITZ & BEAM LAW OFFICES OF HORWITZ & BEAM TWO VENTURE PLAZA SUITE 380 IRVINE, CALIFORNIA 92618 (714) 453-0300 (310) 842-8574 FAX: (714) 453-9416 Gregory B. Beam, Esq. Lawrence W. Horwitz, Esq. Lawrence R. Bujold, Esq. Lawrence M. Cron, Esq. Lynne Bolduc, Esq. Thomas B. Griffen, Esq. John J. Isaza, Esq. Malea M. Farsai, Esq. April 21, 1997 Securities and Exchange Commission 450 Fifth Street, N.W. Judiciary Plaza Washington, DC 20549 Re: CRYO-CELL INTERNATIONAL, INC. Ladies and Gentlemen: This office represents CRYO-CELL INTERNATIONAL, INC., a Nevada corporation (the "Registrant") in connection with the Registrant's Registration Statement on Form S-8 under the Securities Act of 1933 (the "Registration Statement"), which relates to the registration of a total of 10,000 shares of the Registrant's Common Stock issuable upon exercise of options issued to Horwitz & Beam for performance of certain legal representation, advisory, and counseling services (the "Registered Securities"). In connection with our representation, we have examined such documents and undertaken such further inquiry as we consider necessary for rendering the opinion hereinafter set forth. Based upon the foregoing, it is our opinion that the Registered Securities, when sold as set forth in the Registration Statement, will be legally issued, fully paid and nonassessable. We acknowledge that we are referred to under the heading "Legal Matters" in the Prospectus which is a part of the Registrant's Form S-8 Registration Statement relating to the Registered Securities, and we hereby consent to such use of our name in such Registration Statement and to the filing of this opinion as Exhibit 5 to the Registration Statement and with such state regulatory agencies in such states as may require such filing in connection with the registration of the Registered Securities for offer and sale in such states. HORWITZ & BEAM